Tetrahydropyran - Wikipedia
WEBTetrahydropyran (THP) is the organic compound consisting of a saturated six-membered ring containing five carbon atoms and one oxygen atom. It is named by reference to pyran, which contains two double bonds, and may be produced from it by adding four hydrogens. In 2013, its preferred IUPAC name was established as oxane. [1]
Understanding Tetrahydropyranyl as a Protecting Group in …
WEBMar 8, 2017 · Tetrahydropyranyl (Thp) is recognized as a useful protecting group for alcohols in organic synthesis. It has several advantages, including low cost, ease of introduction, general stability to most non‐acidic reagents, it confers good solubility, and the ease with which it can be removed if the functional group it protects requires manipulation.
Tetrahydropyranyl ethers - Organic Chemistry Portal
WEBThe tetrahydropyranyl ether is a useful protecting group for the protection of alcohols and phenols, offering stability towards strongly basic reaction conditions, organometallics, hydrides, acylating reagents and alkylation reagents.
Tamm–Horsfall Protein is a Potent Immunomodulatory Molecule and a ...
WEBJan 22, 2018 · THP is a crucial defense molecule in the urinary system against infections, intrinsic offending molecules, and damaged kidney-induced inflammation.
Illustrated Glossary of Organic Chemistry - Tetrahydropyran (THP)
WEBTetrahydropyran (THP): A saturated heterocyclic ring containing five sp 3 carbon atoms and one sp 3 oxygen atom having the molecular structure shown below, or a molecule containing this moiety. Most frequently encountered in pyranose carbohydrates, or as an alcohol protecting group.
Tetrahydropyranyl: A Non‐aromatic, Mild‐Acid‐Labile Group for …
WEBMar 8, 2017 · The use of the tetrahydropyranyl (Thp) group for the protection of serine and threonine side-chain hydroxyl groups in solid-phase peptide synthesis has not been widely investigated. Ser/Thr side-chain hydroxyl protection with this acid-labile and non-aromatic moiety is presented here.
The Chemistry and Pharmacology of Tetrahydropyridines: Part 2
WEBTetrahydropyridines (THPs) have sparked notable interest as an auspicious heterocyclic moiety. Existing in distinct structural isomers including 1,2,3,4-tetrahydropyridine, 1,2,3,6-tetrahydropyridine, 2,3,4,5-tetrahydropyridine, its presence has been identified in both natural products and synthetic pharmaceutical agents.
Synthesis of Saturated Tetrahydropyrans | SpringerLink
WEBDec 10, 2013 · Tetrahydropyran (THP) rings are important motifs in biologically active molecules. This review presents common strategies for THP synthesis based on typical retrosynthetic disconnections. General mechanistic and stereochemical considerations for each disconnection are included.
Tamm‐Horsfall protein: a multilayered defence molecule against urinary ...
WEBApr 7, 2005 · With the identification of THP to potently mediate immunomodulatory effects as a soluble molecule exclusively existing in the urinary tract, an important role has been assigned to this most abundant protein in mammalian urine.
Tamm-Horsfall Protein is a Potent Immunomodulatory Molecule …
WEBJan 22, 2018 · Tamm-Horsfall protein (THP), or uromodulin (UMOD), is an 80-90-kDa phosphatidylinositol-anchored glycoprotein produced exclusively by the renal tubular cells in the thick ascending limb of the loop of Henle. Physiologically, THP is implicated in renal countercurrent gradient formation, sodium homeos ….