Pope Francis has named the first woman to head a major Vatican office. ROME (AP) — Pope Francis on Monday named the first woman to head a major Vatican office, appointing an Italian nun, Sister Simona Brambilla, to become prefect of the department responsible for all the Catholic Church's religious orders.

Sister Simona Brambilla was appointed as the prefect of a Vatican office that oversees religious orders, but she may not be alone at the top.

Francis’ liberal pick for Washington, D.C. archbishop is at odds with Trump’s choice for ambassador to the Vatican, Brian Burch, a vocal Francis critic.