During Mr. Trump's first term, his labor secretary, Alexander Acosta, resigned following criticism of his handling of Epstein's 2008 plea deal when he was a federal prosecutor in Florida. Epstein served 13 months in a jail work-release program after he was originally accused of sexually abusing dozens of girls and young women.

White House aides have made it clear that no one in the administration is allowed to talk about Epstein without high-level vetting as Trump attempts to change the subject.

President Trump told reporters they need to worry less about his connection to Jeffrey Epstein and focus on others

Any time I say anything about Epstein, they’re like, ‘Why didn’t Joe Biden’s — why didn’t Joe Biden release the files?’ And this is what I say: Have you met Merrick Garland?” Tanden

The case of Jeffrey Epstein, sex offender and former friend of the president, has blown up into a major headache for the White House.

The satirical animated show parodied Trump over the Epstein files and other issues, sparking a stern response from the White House. The July 23 episode took multiple shots at the US President, including a depiction of him being in bed with Satan. The South Park Trump referenced the GOP leader and his recent comments about Jeffrey Epstein.