You want upsets? We've got upsets. Multiple underdogs defeated the favorite in Week 5 of the 2025 NFL season. Continue reading to find a full list of the teams that defied the odds.

The Bengals are throwing in the towel on Jake Browning after trading for Joe Flacco. The veteran passer struggled in Cleveland but could still be an upgrade for Ja'Marr Chase and Tee Higgins.

Next Gen Stats Insight for Texans-Ravens (via NFL Pro):  Nick Chubb  rushed for 61 yards on 11 carries with one touchdown, generating +33 rushing yards over expected. This marks his highest RYOE output this season and his most since Week 17, 2022.

SportsLine's top NFL experts reveal their NFL picks, NFL predictions, NFL betting tips and NFL best bets for Week 5

Stefon Diggs got his revenge against the Bills and Trevor Lawrence continued to show it's OK to be lucky, while Aaron Glenn hasn't had the same fortune with the Jets and Saquon Barkley hasn't been the same player this year.

Now five weeks into the 2025 NFL campaign, a large enough sample size allows everyone to believe in what they've seen to date. The Tampa Bay Buccaneers' Baker Mayfield should be atop the early MVP discussions.

The Buffalo Bills are no longer unbeaten as they fell to the New England Patriots in Week 5, 23-20 at Highmark Stadium. The loss snaps a 14-game home-winning streak for the Bills. Sometimes the stats can tell the story of who performed well and who did not, but Pro Football Focus is there to provide a little bit more context.

Tonight's Sunday Night Football game features an AFC thriller as the New England Patriots take on the Buffalo Bills. Live coverage begins at 7 PM ET.

SportsLine AI evaluated the Week 5 NFL odds and revealed its NFL predictions, NFL score predictions and NFL betting picks for every game

As good as Darnold was, Tampa Bay quarterback Baker Mayfield was even better, going 29-for-33 for 379 yards and two touchdowns. His 11-yard touchdown pass to Sterling Shephard with 1:08 to play tied the score at 35 and set the stage for the win.

The Kansas City Chiefs dropped their third game of the 2025 NFL season, falling to 2-3 overall with a 31-28 loss to the Jacksonville Jaguars on "Monday Night Football." Penalties were a massive problem in Week 5 against the Jags,