In 1921, Otto Loewi woke from a dream with the idea for an experiment that proved nerves communicate using chemicals, not just electricity. By showing that stimulating one frog’s heart released a ...

Figure 2: Human alpha cells express vAChT and ChAT. Figure 3: Isolated human islets secrete acetylcholine (ACh) in response to alpha cell–specific stimuli. We further used the biosensor assay to ...

Memopezil is at the center of a rapidly growing conversation about cognitive health in 2026, as consumer interest in brain support has reached an all-time high, with search volume for terms like ...

Attention is a rich and complex psychological and neurobiological construct. In both non-human 1,2,3,4 and human primates 7, researchers have investigated a wealth of paradigms tapping visual ...

Acetylcholine regulates blood flow, but the source of blood acetylcholine has been unclear. Now, researchers at Karolinska Institutet have discovered that certain T cells in human blood can produce ...

Acetylcholine (ACh) rechallenge may be a novel method to improve detection of coexisting coronary spasm endotypes, and at the same time, assess the treatment response to nitrate-based therapies, a new ...

More than 60% of complement inhibitor–naive patients with acetylcholine receptor–positive generalized myasthenia gravis (MG) in diverse clinical populations had a clinically meaningful reduction in MG ...

Cocaine, opioids, and other drugs of abuse disrupt the brain's reward system, often shifting users' priorities to obtaining more drug above all else. For people battling addiction, this persistent ...

Acetylcholine (ACh) is a neuromodulator with a central role in aversive learning - rapid conditioning to unpleasant smell, taste, or touch. These learning functions play out in cells called D2 ...