In epidemiologic studies and disease prevention trials, interest often involves estimation of the relationship between some disease endpoints and individual exposure. In some studies, due to the ...

Investigator: Right, here is the data set. What is the P value? Statistician: Oh, hello again. Look, I have some concerns about how the endpoint was assessed... Investigator: Fine, I'll add a sentence ...

Conventionally, sample size calculations are viewed as calculations determining the right number of subjects needed for a study. Such calculations follow the classical paradigm: "for a difference X, I ...