Brock Purdy, San Francisco surging at right time: Colts vs. 49ers MNF takeaways

Philip Rivers starts again when he takes on the ferocious 49ers on "Monday Night Football." Here's score, highlights, stats ...

49ers Clinch Playoff Spot, Roll Past Colts 48–27 on Monday Night

McCaffrey fuels an offensive powerhouse as the 49ers overpower the Colts, showcasing balance and timely defense en route to a ...

Brock Purdy's career-high five TD passes power 49ers past Philip Rivers' Colts on 'Monday Night Football'

The Week 16 edition of "Monday Night Football" between the Indianapolis Colts (8-7) and the San Francisco 49ers (11-4) will ...

49ers vs Colts: Time, Channel & Free Live Streaming Info for Monday Night Football Now

Caesars Sportsbook pioneered live streaming NFL games in December 2022 by launching its "Watch & Bet" feature for both regular-season and playoff matchups. Since then, Caesars has improved the ...

Instant analysis of 49ers’ 48-27 win over Colts on path toward No. 1 seed

By winning Monday night’s final regular-season road game in a 48-27 shootout over the Colts, the 49ers remained in control of ...

Jonathan Taylor player props and odds | Colts vs. 49ers in week 16 2025

Learn more about for Jonathan Taylor's prop betting lines, stats and more before his Indianapolis Colts play against the San ...
WKYC3

Colts and 49ers head into a key Monday night matchup chasing different playoff aspirations

Monday, 8:15 p.m. EST, ESPN. BetMGM NFL odds: 49ers by 6. Against the spread: 49ers 9-5; Colts 8-6. Series record: Colts lead 27-18. Last meeting: Colts beat 49ers 30-18 on Oct. 24, 2021, in Santa ...