Safety of subcutaneous daratumumab in the treatment of plasma-cell disorders: A single-center experience. Economic evaluation of six and 12 month (m) treatment with isatuximab and carfilzomib and ...

Cytogenetics is the study of chromosomes, a vital tool to understanding how genetics play a role in the development and progression of certain diseases, as well as to predicting how a person will ...

New research shows that Optical Genome Mapping (OGM) detects abnormalities in chromosomes and DNA very quickly, effectively and accurately. Sometimes even better than all existing techniques together, ...

An important aim of recent cytogenetic developments has been to increase resolution. This has been achieved by advances that relate to the two elements of cytogenetic analysis, the target and the ...

Panelists discuss how NCCN guidelines are expected to incorporate quadruplet-based regimens as reasonable treatment approaches for transplant-ineligible patients, while emphasizing the need for ...

It is crucial in the development of cell and gene therapies to understand the impact of the gene editing process on chromosomal structure. When cells are edited, differentiated, modified, or ...

NOTE. Comparison for complexity gives OR/HR between categories for patients with abnormal karyotype only; ORs for CR are calculated using logistic regression, and HRs for EFS, DFS, and OS are ...

Cytogenetics is a field of study that deals with chromosomes and related abnormalities. Chromosome analysis is also known as karyotyping and involves the pairing of homologous chromosomes.

Patients treated with ciltacabtagene autoleucel (cilta-cel; Carvykti) in the phase 3 CARTITUDE-4 trial (NCT04181827) achieved high rates of progression-free survival (PFS) at near ...

The Cytogenetics Laboratory performs chromosome analysis, fluorescence in situ hybridization (FISH), and array comparative genomic hybridization (array CGH) on cells prepared from a wide variety of ...