At its core, aging is a dysfunction in the way DNA is read and implemented in cells, says David Sinclair, PhD. And he’s basically putting all his money on figuring out how to leverage our knowledge of ...

It’s been 13 years in the making, but Dr. David Sinclair and his colleagues have finally answered the question of what drives aging. In a study published Jan. 12 in Cell, Sinclair, a professor of ...

Emerging research suggests that lifestyle factors including exercise, nutrition and heat exposure may influence the cellular pathways that drive aging. Most of us learned that aging results from the ...

Universal” biological signatures of aging shared across different mammalian species—including humans—could offer new clues to ...

Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes. The breakthrough ...