Achondroplasia, associated with gain-of-function mutations in FGFR3, causes growth plate cartilage dysfunction, resulting in short-limb dwarfism. However, its precise molecular and cellular mechanisms ...

Endochondral bone regeneration mimics the natural process by which cartilage templates are formed and subsequently remodelled into bone. This developmental engineering approach relies on chondrogenic ...

Synchrotron imaging of a Devonian stem lungfish reveals pectoral fin bones formed by a unique mix of two endochondral ...