A longstanding question in neuroscience is how mammalian brains (including ours) adapt to external environments, information, and experiences. In a paradigm-shifting study published in Nature, ...

Wanting to better understand how the brain forms and stores long-term memory, an international team of scientists undertook a study of the brain's circuits. Their work sheds new light on the way the ...

The entorhinal cortex is a sliver of brain tissue no bigger than a postage stamp, tucked just in front of the hippocampus. It ...

Researchers have discovered the mechanistic steps underlying a new type of synaptic plasticity called behavioral timescale synaptic plasticity (BTSP). The study reveals how the entorhinal cortex (EC) ...

Neurons in an area of the brain responsible for memory were significantly larger in SuperAgers compared to cognitively average peers, individuals with early-stage Alzheimer's disease and even ...

The representation of stimulus identity and experience is transformed from primary olfactory cortex to memory-related multisensory areas in the hippocampus.

This study illustrates the spatiotemporal dynamics of neuron subtype changes within the entorhinal cortex–hippocampal circuit during Alzheimer’s disease progression. EC-stellate neurons progressively ...

The spread of tau pathology from the entorhinal cortex into the neighboring hippocampus region of the brain is thought to herald the onset of clinical symptoms in AD, but exactly what path does tau ...

Pitolisant, a histamine H3 receptor inverse agonist, improved recognition memory, working memory performance, and ...

A longstanding question in neuroscience is how mammalian brains (including ours) adapt to external environments, information, and experiences. In a paradigm-shifting study published in Nature, ...