Calcium is essential for the correct functioning of the cell and requires regulation to avoid high concentrations causing cell death. Calcium ions are important for cell signaling as the binding of ...

Cerebral malaria kills 1 out of 5 children that suffer from it, and causes long-term disabilities in half of the survivors. Malaria is caused by the parasite Plasmodium falciparum, which reproduces in ...

(Medical Xpress)—Fighting malaria in today's world will require a new, targeted approach, and Virginia Tech researchers are out for blood. The parasites responsible for the mosquito-borne infectious ...

Plasmodium falciparum causes malaria in humans by multiplying first in the liver cells and then in red blood cells. Merozoites or daughter parasites are released as the host cells are destroyed to ...

The virulence of the human malaria parasite Plasmodium falciparum is associated with altered rheological properties of infected erythrocytes 1. Whereas uninfected red blood cells circulate through the ...

Plasmodium falciparum malaria exerts one of the strongest selective pressures on the human genome, driving polymorphisms that modulate infection outcome and disease severity. Immunogenetics in this ...

A major tool against malaria in Africa has been the use of rapid diagnostic tests, which have been part of the "test-treat-track" strategy in Ethiopia, the second most-populated country in Africa. But ...

Gene expression within the apicoplast, an organelle in the malaria parasite Plasmodium falciparum, is regulated by melatonin (the circadian signaling hormone) in host blood and intrinsic parasite cues ...

The evolutionary path of the deadliest human malaria parasite, Plasmodium falciparum, has been revealed for the first time. This parasite is a member of the Laverania parasite family that only infect ...

RGCB study reveals host biology influences malaria treatment failures, suggesting new strategies to enhance drug efficacy and ...

Drugs have been used to treat and prevent malaria for centuries. Bark from the cinchona tree, which contained an array of alkaloids with antimalarial properties, appeared in Western therapeutics in ...

A major tool against malaria in Africa has been the use of rapid diagnostic tests, which have been part of the “test-treat-track” strategy in Ethiopia, the second most-populated country in Africa. But ...