HLA screening assays are used to detect the presence or absence of HLA antibodies and do not typically provide any information on HLA specificity of the detected antibodies. The function of the ...

Among kidney transplant recipients, patients with mostly IgG3 donor-specific HLA antibodies had a higher likelihood of organ rejection soon after transplantation. If rejection occurred in those with ...

End-stage organ diseases are responsible for millions of deaths worldwide each year. Organ transplantation has become the treatment of choice, but despite the 120,000 new organ transplantations ...

Donor-specific antibodies create an immunologic barrier to transplantation. Current therapies to modify donor-specific antibodies are limited and ineffective in the most highly HLA-sensitized patients ...

The Single-antigen Bead (SAB) assay has revolutionized the detection of anti-HLA antibodies, which are critical in transplantation medicine. Despite its advantages, several limitations and challenges ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, No. 22 (Oct. 24, 1995), pp. 10292-10296 (5 pages) A monomorphic anti-HLA-G monoclonal antibody (mAb) was ...

Activation of Myeloid cells and interferon release is an early response to infection. The 3-marker combination (CD169/CD64/HLA-DR) gives an excellent overview of the innate immune response. The flow ...

Inc. (formerly Pure Protein, LLC) today announced the commercial launch of its new soluble HLA-G (sHLA-G) product portfolio, ...

HLA testing has been a staple in transplantation since the recognition that antibodies, directed against lymphocytes, were associated with allograft failure. This seminal finding led to the discovery ...