In this review, we will look ahead and discuss potential future avenues of fluorescence imaging with light-sheets. We will describe how volumetric and temporal imaging barriers limit the application ...

In biology, seeing can lead to understanding, and researchers in Professor Edward Boyden's lab at the McGovern Institute for Brain Research are committed to bringing life into sharper focus. With a ...

The optical microscope has revolutionized biology since at least the 17 th Century. Since then, it has progressed from a largely observational tool to a powerful bioanalytical platform. However, ...

Our brain is a complex organ. Billions of nerve cells are wired in an intricate network, constantly processing signals, enabling us to recall memories or to move our bodies. Making sense of this ...

Hosts of new applications have turned the light microscope into an exquisitely sensitive measuring device that can be used to image dynamic cellular events right down to the molecular level. Indeed, ...

Deep inside a small, windowless room at the University of California, Berkeley, two microscopes are quietly capturing some of the most detailed views of life ever recorded. Day and night, they collect ...

How do photosynthetic organisms harvest light so efficiently? To help answer this question, researchers have developed an ultrafast transient absorption microscope with sensitivity approaching the ...

In a cramped, windowless room on the University of California, Berkeley campus, two bespoke microscopes - each a Swiss Army knife for high-resolution imaging - operate around the clock gathering data ...

The Department of Biology at Saint Louis University offers a Leica SP8 confocal microscope with resonant scanner for academic and commercial use. Live-cell imaging can be performed using a stage ...

In 1931, physicists Knoll and Ruska unveiled the first electron microscope, revolutionizing science by using magnetic lenses ...