Nature

A 52-week prospective, cohort study of the effects of losartan with or without hydrochlorothiazide (HCTZ) in hypertensive patients with metabolic syndrome

The metabolic syndrome represents a specific cluster of phenotypes that increase the risk for coronary heart disease and type-2 diabetes mellitus. 1, 2, 3, 4 Owing to ...
Nature

Safety and benefits of a tablet combining losartan and hydrochlorothiazide in Japanese diabetic patients with hypertension

This study was conducted to determine the effects of a tablet combining losartan/hydrochlorothiazide (L/HCTZ) in comparison with losartan alone in Japanese diabetic patients with hypertension. Thirty ...
Medscape

Combination Angiotensin Receptor Blocker/Hydrochlorothiazide as Initial Therapy in the Treatment of Patients With Severe Hypertension

Patients with severe hypertension are at high risk for cardiovascular events. The authors hypothesized that initial treatment with a combination angiotensin receptor blocker/diuretic agent would be ...
Medscape

Efficacy and Safety of Angiotensin II Receptor Blockers in Elderly Patients With Mild to Moderate Hypertension

Chika E. Okereke, MD; Franz H. Messerli, MD, Department of Internal Medicine, Section on Hypertensive Diseases, Ochsner Clinic and Alton Ochsner Medical Foundation, New Orleans, LA A total of 57% of ...