Purpose: In contrast to its high prevalence in Caucasians, medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is reported to be an extremely rare metabolic disorder in the Asian population. The ...

In the expanded newborn screening era, diagnosis of MCAD deficiency on clinical grounds alone is less common, although symptoms can occur in the early neonatal period before the results of newborn ...

Medium-chain acyl–coenzyme A dehydrogenase (MCAD) deficiency is the most frequently diagnosed defect in mitochondrial beta-oxidation, with a prevalence of 1 case per 15,000 persons in the United ...

Dutch researcher Terry Derks has demonstrated that the metabolic disease MCAD deficiency can be detected at an early stage. At present the disease is only found in half of the expected number of ...

Simple blood tests can now detect obscure genetic diseases that may be deadly in newborns, but there's a debate over whether all the tests are worthwhile. INDEPTH: Newborn screening FAQs Canadian ...

In several populations, the 985G>A carrier frequency is determined (for an overview, see Wang et al 7) and from these studies it can be observed that the distribution pattern of this mutation shows a ...

HOUSTON - Researchers at The University of Texas MD Anderson Cancer Center have discovered a novel function for the metabolic enzyme medium-chain acyl-CoA dehydrogenase (MCAD) in glioblastoma (GBM).

Scientists at the University of Texas MD Anderson Cancer Center say have discovered a novel function for the metabolic enzyme medium-chain acyl-CoA dehydrogenase (MCAD) in glioblastoma (GBM). MCAD ...

Researchers at The University of Texas MD Anderson Cancer Center have discovered a novel function for the metabolic enzyme medium-chain acyl-CoA dehydrogenase (MCAD) in glioblastoma (GBM). MCAD ...

MCAD deficiency, like other inborn errors of metabolism, is increasingly recognized not as a dichotomous condition but rather as a spectrum of enzyme deficiency states caused by different mutations in ...