Recently, a research group from Hefei Institutes of Physical Science (HFIPS) of Chinese Academy of Sciences (CAS) and The Second Hospital of Anhui Medical University dissected, for the first time, the ...
Clinicopathologic data from a population-based endometrial cancer cohort, unselected for age or family history, were analyzed to determine the optimal scheme for identification of patients with ...
Background Tumour testing for microsatellite instability (MSI) or mismatch repair deficiency (dMMR) is used to screen for ...
Introduction: Lynch syndrome (LS) is an autosomal dominant cancer predisposition syndrome caused by germline mutations in mismatch repair (MMR) genes, associated with various malignancies including ...
After learning that I had Lynch syndrome and a MLH1 mutation, I changed my lifestyle to hopefully prevent a cancer diagnosis. After meeting with a genetic counselor, undergoing genetic testing for ...
Population-level identification of patients with MMR mutation-positive endometrial cancer is optimized by stepwise testing for tumor MMR IHC loss in patients younger than 60 years, tumor MLH1 ...
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