A designer version of the tau protein, developed by a team led by UT Southwestern Medical Center researchers, maintains its ...

The aging brains of people with Alzheimer’s, Parkinson’s and other neurodegenerative diseases are suffused with telltale aggregates of proteins in or around their neurons. How these protein clumps ...

Could measuring protein clumps in our cells be a new way to find out our risk of getting age-related diseases? Professor Dorothee Dormann and Professor Edward Lemke of Johannes Gutenberg University ...

Researchers have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation in specific tissues when normal methods of molecular monitoring fail.

Durable analytical instruments expedite the study of misfolded proteins linked to neurodegenerative diseases. To overcome these limitations, scientists developed the real-time quaking-induced ...

Researchers at the VIB-KU Leuven Center for Microbiology and the VIB-KU Leuven Center for Brain & Disease Research revealed a mechanism involving protein aggregation that allows bacteria to enter a ...

Protein low-complexity domains (LCDs) stack together to form dynamic liquid droplets within the cell; alas, some pathogenic mutations in these regions encourage aggregation beyond this temporary ...

The pathway leading to the telltale sign of ALS, protein aggregation in the cytoplasm of motor neurons, has been revealed. Researchers from the University of California – San Diego (CA, USA) have ...

Researchers have developed a 'self-driving' microscope that can predict the onset of misfolded protein aggregation - a hallmark of neurodegenerative disease - as well as analyze the biomechanical ...

The accumulation of misfolded proteins in the brain is central to the progression of neurodegenerative diseases like Huntington’s, Alzheimer’s and Parkinson’s. But to the human eye, proteins that are ...