Protein activity can be precisely regulated via subtle changes in temperature using heat-sensitive switches. Underlying this ...

For decades, researchers have used that green fluorescent protein and similar molecules to light up the field of biology, tracking what’s happening inside cells. Now these ubiquitous tools are ...

Houston Methodist scientists have uncovered an unexpected side of a protein best known for its link to brain diseases. The ...

A team led by researchers at the University of Cologne has identified a protein called ANKIB1 that acts as a volume dial for the body’s frontline immune defenses, controlling how strongly cells ...

A new study discovers how nitric oxide triggers a biochemical domino effect in the brain, leading to mTOR overactivation in ...

Intrinsically disordered proteins lack a fixed structure, which is why they have been considered "undruggable" targets for ...

Researchers at the National University of Singapore (NUS) have identified a protein called tyrosine phosphatase 1B (PTP1B) as ...

Neurodegenerative disorders such as Alzheimer's disease (AD) are typically diagnosed after irreversible pathology has developed. Aging, the strongest risk factor, drives molecular changes that ...

Targeted protein degradation tricks the internal machinery of cells in weeds to destroy proteins that are essential to their survival.