Recently, a genome-wide biallelic linkage map of Saccharomyces cerevisiae has been constructed based on the direct hybridization of whole genomic DNA from two polymorphic strains to high-density ...

Association studies that correlate SNP patterns to disease risks are straightforward. Clues to the past can be subtler, but they are found at all levels of evolution--from the great branching points ...

If the concept of personalized medicine is to be realized, it is increasingly clear that single nucleotide polymorphisms (SNPs), the most common genetic variations between human beings, will be a key ...

Take any two individuals, sequence and compare their genomic DNA, and you'll find that the vast majority (about 99.9%) of the sequences are identical. In the remaining 0.1% lie differences in disease ...

As more bacterial DNA sequences are identified, the computational challenges associated with whole-genome sequencing have researchers looking to other potential methods of tracking and understanding ...

Through the Human Genome Project, the HapMap Project and other efforts, we are beginning to identify genes that are modified in some diseases. More difficult to measure and identify are the regulatory ...

A thorough and accurate characterization of both sequences and phenotypic variation is necessary for a detailed comprehension of how variations in the human genome's sequence influence phenotypic ...

MADISON, Wis.--(BUSINESS WIRE)-- Sequence Capture technology was pioneered by Roche NimbleGen (Pink Sheets: RHHBY) (SWX:RO) (SWX:ROG) with the initial products focused on human research. Subsequent ...