How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...
In a recent study published in Nature, a group of researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into messenger ribonucleic acids (mRNAs) affects ribosomal ...
SMRTS, a smart mRNA system, enables cell‑selective gene expression, expanding the mRNA toolbox for precision cancer therapies.
Unlocking the therapeutic applicability of LNP-mRNA: chemistry, formulation, and clinical strategies
LNP as the novel drug delivery system enhancing mRNA therapeutic efficacy has been proved for its delivery ability. This review provides valuable insights into the current state-of-the-art of LNP mRNA ...
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First-of-its-kind mRNA system switches on therapeutic genes inside targeted cells
Researchers at the Icahn School of Medicine at Mount Sinai have developed a first-of-its-kind mRNA system that switches on therapeutic genes preferentially inside targeted cells-an advance ...
Aside from maybe high school biology classes, the first time many people heard of mRNA was during the pandemic because of the vital role MRNA technology played in COVID-19 vaccines.
Mount Sinai researchers developed a first-in-class cell-selective modRNA translation system that turns therapeutic genes on ...
Creative Biolabs optimizes the mRNA drug development model by integrating sequence design, RNA-protein interaction ...
Adding a photocopier gene to mRNA vaccines could make them last longer and curb side effects. This article first appeared in The Checkup, MIT Technology Review's weekly biotech newsletter. To receive ...
Vaccines that resemble viruses generally produce a stronger immune response, while mRNA versions are much quicker and cheaper to make. Now we are getting the best of both worlds, in the form of mRNA ...
With the U.S. Health and Human Services Secretary Robert F. Kennedy, Jr. canceling nearly $500 million in mRNA vaccine research contracts on Tuesday, you may be wondering if mRNA vaccines are safe.
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