Polysubstance use disorder is a mental health condition in which someone uses more than one substance at the same time or within a short period of time, despite a pattern of negative effects.

U.S. overdose deaths involving polysubstance use—particularly opioids combined with stimulants—have risen sharply in recent years, with disproportionate increases among non-Hispanic Black and Hispanic ...

A massive survey recently released by a national drug-testing company strongly suggests we are well into the “fourth wave” of the opioid crisis. The three previous waves were driven by 1) prescription ...

Disproportionate increases seen across Black and Hispanic individuals, particularly in opioid-stimulant and opioid-only profiles. (HealthDay News) — Overdose deaths from polysubstance use escalated ...

Recreational use of substances such as cannabis, MDMA and cocaine is thought to harm the neurotransmitter communication networks that coordinate many memory processes that support autobiographical ...

Mixing drugs, also known as polysubstance use, occurs when two or more drugs are taken together or within a short time period, intentionally or unintentionally. Even if someone has mixed drugs before, ...

PWH with substance use face increased risks of housing instability, food insecurity, and transportation issues compared to controls. Polysubstance users have higher odds of depression, mania, and ...