Factor deficiency or inhibition. The possible causes of the isolated prolonged aPTT in this case include factor deficiencies and factor inhibitors. Prolongation of both the PT and aPTT suggests ...

Changes Clinical Practice: Screening for lupus anticoagulant (LA) should be limited to two tests that represent two different assay principles. The Dilute Russell Viper Venom Time (dRVVT) and ...

Target-specific oral anticoagulants have emerged as alternative therapeutic options for the management of thrombembolic disorders. Before the development of target-specific oral anticoagulants (TSOACs ...

Objectives: The activated partial thromboplastin time (aPTT) test has been used for years to monitor parenteral direct thrombin inhibitors (DTIs) and unfractionated heparin. Results: The aPTT ...

Activated Partial Thromboplastin Time (aPTT or APTT): is a medical test that characterizes blood coagulation. Partial thromboplastin time (PTT) measures the overall speed at which blood clots by means ...

The dilute Russell viper venom time (dRVVT), combined with the activated partial thromboplastin time (APTT) test, is widely regarded as a standard method for LA detection. However, these assays can be ...

There are several lab tests for hemophilia. However, the main tests detect the clotting activity of factors VIII and IX, which are proteins in the blood. Hemophilia is a bleeding disorder in which an ...