As the first Latino secretary of state, Sen. Marco Rubio is expected to devote considerable attention to what has long been disparagingly referred to as Washington’s backyard.

The three-term senator from Florida viciously criticized Donald J. Trump during the 2016 campaign but has since ingratiated himself and become a foreign policy adviser to Mr. Trump.

With Marco Rubio picked to be secretary of state, Gov. Ron DeSantis now must pick his replacement in the U.S. Senate.