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Adding the PD-1 inhibitor pembrolizumab to chemoradiotherapy for high-risk, locally advanced cervical cancer significantly improves patients’ overall survival compared to treatment with CRT alone.
University of Nebraska Medical Center, Omaha, NE, ...
This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license. This work is licensed under a Creative Commons ...
Program of Immunology and Immunotherapy, Cima Universidad de Navarra, Pamplona, Spain.
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UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.
Major Finding: Post-fast refeeding contributes to Lgr5 + intestinal stem cell proliferation and tumor formation. Concept: An mTORC1–polyamine–protein synthesis axis drives refeeding-associated ...
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Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Two HER2-targeted tyrosine kinase inhibitors, BAY 29270078 and zongertinib, each showed robust efficacy and safety in early phase. Patients experienced significant tumor shrinkage rates, and the ...