Background Bronchoalveolar lavage (BAL) is essential in determining the efficacy of novel therapies in alpha-1 antitrypsin deficiency (AATD). These require initial proof-of-concept demonstration that ...
Introduction There has been a marked increase in vaping in the UK since 2012 and in children between 2018–2021. Anecdotal reports from those working directly with children and young people indicate ...
Introduction The number of computed tomography guided biopsies (CTGB) performed to investigate lung cancer is increasing. Data regarding performance and complications are important to inform patient ...
Rationale Endoscopic lung volume reduction improves lung function, quality of life and exercise capacity in severe emphysema patients. However, its effect on the diaphragm function is not well ...
Background Patient perception of asthma treatment is rarely captured, and no specific tools exist to measure it. We developed an inhouse severe asthma patient feedback questionnaire (SAPFQ) using ...
Introduction and Objectives Oral corticosteroids (OCS) are sometimes used to manage exacerbations in patients with chronic obstructive pulmonary disease (COPD). Evidence suggests chronic OCS use is ...
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Asthma exacerbations are common. They account for a significant morbidity and contribute a disproportionate amount to the cost of asthma management. The optimal strategies for the prevention of asthma ...
Background: Oxidative stress is thought to have a major role in the pathogenesis of airway obstruction. A study was undertaken to determine whether subjects with low levels of antioxidants (serum ...
BACKGROUND In a retrospective study the value of bronchoalveolar lavage (BAL) in the diagnosis of pneumonia was investigated in 95 immunocompromised patients suffering from haematological disorders ...
Background Smoking and severe asthma exacerbations in pregnancy are risk factors for low birth weight babies. No studies have assessed the clinical implications of smoking on asthma exacerbations in ...
1 Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong 2 Department of Psychiatry, Shatin Hospital, The Chinese University of Hong Kong, Shatin, ...