For decades, the biology of the intestinal stem cells was considered analogous to that of well-studied hematopoietic stem ...

The protein expression profile of ACE2, suggested as host receptor for SARS‐CoV‐2, is assessed in various human organs. Notably, limited ACE2 expression is observed in the respiratory system both on ...

Stress granules are an integral part of the stress response that are formed from non-translating mRNAs aggregated with proteins. While much is known about stress granules, the factors that drive their ...

This study explores how mechanical signaling through membrane tension induces somal translocation during neuronal migration.

Poorly energized mitochondria trap a subpopulation of mitochondrial precursor proteins in the intermembrane space. This article introduces ‘mitochondrial triage of precursor proteins’ (MitoTraP) as a ...

For decades microtubule-targeting agents (MTAs) have been a cornerstone of cancer treatment regimens and continue to be heavily employed as backbone chemotherapy in combination with new targeted ...

Treatment of sensitive bacteria with beta‐lactam antibiotics often leads to two salient population‐level features: a transient increase in total population biomass before a subsequent decline, and a ...

The migratory cardiac neural crest cells (CNCCs) contribute greatly to cardiovascular development. A thorough understanding of the cell lineages, developmental chronology, and transcriptomic states of ...

Uncapped free 20S proteasomes are abundant and active in cells, and yet their degraded intracellular protein substrates have remained underexplored. In their recent study, Sharon and colleagues ...

Immunocytokines, comprising various antibody formats and cytokines, have been reported for cancer therapy (Gout et al, 2022). Targeting efficacy was shown to be determined not only by the antibody but ...

The highly conserved Kinase, Endopeptidase and Other Proteins of small Size (KEOPS)/Endopeptidase‐like and Kinase associated to transcribed Chromatin (EKC) protein complex has been implicated in ...

Two‐pore domain potassium (K2P) channels comprise a major and structurally distinct subset of the mammalian K + channel superfamily (Enyedi and Czirjak, 2010). The human genome contains 15 K2P channel ...