As blood stem cells age, their lysosomes become overactive and damaged, triggering inflammation and weakening the body’s ...
A novel approach using a lysosomal enzyme to prevent and reverse amyloid accumulation inside as well as outside neurons, with greater potency, ...
To investigate the role of KIF13B in SICD, a research team led by Prof. Xunde Xian from Peking University conducted a series ...
BACKGROUND: Pulmonary hypertension (PH) is a serious complication of heart failure with preserved ejection fraction (HFpEF), ...
Impaired mitophagy and the accumulation of damaged mitochondria are key drivers of endothelial cell (EC)dysfunction in ...
Every drug approved for Parkinson’s disease does the same thing: it manages symptoms. None slows the underlying destruction ...
New cellular defense: Microglia can form tunneling nanotubes to clear toxic alpha-synuclein and supply healthy mitochondria to neurons in lab studies. Therapies in pipeline: Experimental GCase ...