Nature

A human telomerase reverse transcriptase-derived peptide GV1001 rescues neurodegeneration in a mouse model of Alzheimer disease

GV1001 is a peptide consisting of 16 amino acids derived from the catalytic subunit of human telomerase reverse transcriptase. A recent phase II clinical trial in patients with Alzheimer disease (AD) ...
Nature

Nociceptor circadian clock genes control excitability and pain perception in mice in a sex- and time-dependent manner

The authors thank Dr. Merritt Maduke (Dept of Molecular and Cellular Physiology, Stanford University) for advice regarding the use of AK-42, and Drs. Charles W. Bourque (McGill University) and Yves de ...
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Jackass: Best and Last Audience Reviews: A Bittersweet but Laugh-Out-Loud Funny Goodbye Link to Jackass: Best and Last Audience Reviews: A Bittersweet but Laugh-Out-Loud Funny Goodbye Jackass: Best ...
PC Magazine

Valve Confirms Steam Machine Will Cost Over $1,000. Here's How to Buy One

Valve Confirms Steam Machine Will Cost Over $1,000. Here's How to Buy One The 512GB version will cost $1,049, while the 2TB version is $1,349. You can sign up now to join a waiting list, with orders ...