Mount Sinai scientists analyzed over 12,000 brain proteins, uncovering how neuron–glia communication failures drive Alzheimer’s disease. They identified AHNAK as a key protein whose activity rises ...

Higher activity of PGC-1α enables brown fat cells in females to thermogenic activity and energy expenditure compared to males, reveals a study conducted in Japan. This research demonstrates that ...

A new study led by the Icahn School of Medicine at Mount Sinai offers one of the most comprehensive views yet of how brain cells interact in Alzheimer's disease, mapping protein networks that reveal ...

Multi-omics integration enhances understanding of biological systems, revealing complex interactions through spatial transcriptomics and epigenetic regulation.

Recent research indicates that the spatial architecture of membrane proteins is crucial for regulating T-cell signaling and activation. 3-5 In the context of CAR T cells, the nanoscale localization ...

Institute researchers have developed a new multi-omics method enabling the profiling of multiple histone modifications and gene expression in single cells. The technique provides high sensitivity, ...