The Niners are lost All-Pro running back Christian McCaffrey and star receiver Deebo Samuel to injuries before Kittle ...

Defensive coordinator Nick Sorensen and run game coordinator and offensive line coach Chris Foerster reviewed the 49ers ...

By creating a numbers advantage in the stands, 49ers fans allow quarterback Brock Purdy and the rest of San Francisco's ...

The San Francisco 49ers have been hit hard by the injury bug this year, but one star player and former Pro Bowler is aiming ...

With McCaffrey and Samuel out, Rams brace for 49ers' cunning tactics. Kobie Turner stresses the need for execution.

San Francisco 49ers tight end George Kittle may miss Week 3's matchup with the Los Angeles Rams after missing Thursday's ...

Already without two of their most important players, the San Francisco 49ers added two more key names to the injury report ...

San Francisco 49ers tight end George Kittle might miss Week 3's game with a hamstring. View the 49ers TE depth chart inside.