The Arizona Cardinals, along with the rest of the NFL, must trim their rosters to 53 players by Tuesday afternoon. One thing that will factor into decisions will be injuries to players. Two reserves are commonly used for injured players and have different functions. There is the PUP (physically unable to perform) reserve and also injured reserve.

The NFL continues to reveal players in the yearly offseason "NFL Top 100." Three Arizona Cardinals players made the list, with linebacker Josh Sweat at No. 95, tight end Trey McBride at No. 65 and safety Budda Baker at No. 34, making the list for the sixth straight year. Several players the Cardinals will face in 2025 continue to be revealed.