Being without Brock Purdy against the Green Bay Packers stung the San Francisco 49ers. It essentially chalked up the game as a loss for the 49ers before they ev ...

Should I drop Deebo Samuel for fantasy football Week 13? Is Deebo Samuel a safe player to cut? Read the fantasy football ...

The Buffalo Bills are fresh off of their bye week heading into a Sunday Night Football matchup with the San Francisco 49ers, ...

San Francisco 49ers quarterback Brock Purdy is the latest star to receive a positive "PupTalk" from the characters of Nickelodeon's PAW Patrol.

The 49ers travel to Buffalo to take on the AFC East-leading Buffalo Bills. Check out our best bet for the game ...

San Francisco 49ers quarterback and Iowa State alum Brock Purdy is showing promising signs after being injured on Nov. 17.

Getting blown out at Green Bay following another squandered late lead the previous week against Seattle has quickly turned ...

The 49ers keep losing key players to injuries. The latest one who could miss time is rookie right guard Dominick Puni. He ...

San Francisco 49ers head coach Kyle Shanahan spoke with reporters via a conference call on Monday, providing several injury ...

San Francisco has put up a combined 27 points the past two weeks and faces a Bills defense great at generating pressure with ...

San Francisco quarterback Brock Purdy took part in some light throwing on Monday after missing his first career game because ...

The Buffalo Bills' upcoming opponent, the San Francisco 49ers, provided a big injury update for their starting quarterback ...