Background Bronchoalveolar lavage (BAL) is essential in determining the efficacy of novel therapies in alpha-1 antitrypsin deficiency (AATD). These require initial proof-of-concept demonstration that ...

Introduction There has been a marked increase in vaping in the UK since 2012 and in children between 2018–2021. Anecdotal reports from those working directly with children and young people indicate ...

Rationale Endoscopic lung volume reduction improves lung function, quality of life and exercise capacity in severe emphysema patients. However, its effect on the diaphragm function is not well ...

Background Patient perception of asthma treatment is rarely captured, and no specific tools exist to measure it. We developed an inhouse severe asthma patient feedback questionnaire (SAPFQ) using ...

Introduction and Objectives Oral corticosteroids (OCS) are sometimes used to manage exacerbations in patients with chronic obstructive pulmonary disease (COPD). Evidence suggests chronic OCS use is ...

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BACKGROUND In a retrospective study the value of bronchoalveolar lavage (BAL) in the diagnosis of pneumonia was investigated in 95 immunocompromised patients suffering from haematological disorders ...

Introduction The number of computed tomography guided biopsies (CTGB) performed to investigate lung cancer is increasing. Data regarding performance and complications are important to inform patient ...

Introduction Bronchiectasis is a chronic, progressive lung condition which has significant effects on quality of life (QOL). Quick patient reported outcome measures (PROMs) measuring QOL are limited ...

Background Exacerbations of chronic obstructive pulmonary disease (COPD) are characterised by increased dyspnoea, reduced quality of life and muscle weakness. Re-exacerbation and hospital admission ...

2 Department of Respiratory Medicine, National Heart and Lung Division, Imperial College, London W2 1PG, UK Correspondence to: Dr med J Schwarze Department of Respiratory Medicine, National Heart and ...

Introduction Guidelines for the follow-up of pulmonary nodules, such as those from the British Thoracic Society, often see compliance rates below 50% in the UK and abroad. However, it is important to ...