Background Bronchoalveolar lavage (BAL) is essential in determining the efficacy of novel therapies in alpha-1 antitrypsin deficiency (AATD). These require initial proof-of-concept demonstration that ...
Introduction There has been a marked increase in vaping in the UK since 2012 and in children between 2018–2021. Anecdotal reports from those working directly with children and young people indicate ...
Rationale Endoscopic lung volume reduction improves lung function, quality of life and exercise capacity in severe emphysema patients. However, its effect on the diaphragm function is not well ...
Background Patient perception of asthma treatment is rarely captured, and no specific tools exist to measure it. We developed an inhouse severe asthma patient feedback questionnaire (SAPFQ) using ...
Introduction and Objectives Oral corticosteroids (OCS) are sometimes used to manage exacerbations in patients with chronic obstructive pulmonary disease (COPD). Evidence suggests chronic OCS use is ...
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Asthma exacerbations are common. They account for a significant morbidity and contribute a disproportionate amount to the cost of asthma management. The optimal strategies for the prevention of asthma ...
BACKGROUND In a retrospective study the value of bronchoalveolar lavage (BAL) in the diagnosis of pneumonia was investigated in 95 immunocompromised patients suffering from haematological disorders ...
Background Smoking and severe asthma exacerbations in pregnancy are risk factors for low birth weight babies. No studies have assessed the clinical implications of smoking on asthma exacerbations in ...
Introduction The number of computed tomography guided biopsies (CTGB) performed to investigate lung cancer is increasing. Data regarding performance and complications are important to inform patient ...
Introduction Bronchiectasis is a chronic, progressive lung condition which has significant effects on quality of life (QOL). Quick patient reported outcome measures (PROMs) measuring QOL are limited ...
Introduction The Great Britain (GB) Asbestos Workers’ Survey is one of the longest running occupational health cohorts in the world. It aims to monitor the long-term health of people who work in the ...
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