The 49ers travel to Buffalo to take on the AFC East-leading Buffalo Bills. Check out our best bet for the game ...

Our top pick for the 49ers vs. Bills Week 13 NFL matchup is to bet on the 49ers +6.5 (+100). This betting advice is ...

The offensive line of the San Francisco 49ers hasn't been too shabby this season. But that doesn't mean they can't use some ...

The Buffalo Bills are fresh off of their bye week heading into a Sunday Night Football matchup with the San Francisco 49ers, ...

The Packers dominated the 49ers 38-10, highlighting major defensive issues and lackluster player performance. San Francisco ...

The San Francisco 49ers might be in the market for an interior defensive lineman in 2025, especially in the wake of the ...

Being without Brock Purdy against the Green Bay Packers stung the San Francisco 49ers. It essentially chalked up the game as ...

The Dolphins defense has been a bright spot so far in 2024 and this offseason they are predicted to add a key piece from the ...

The San Francisco 49ers are in last in the NFC West, and have struggled with injuries all season. Colin Cowherd says that ...

After a frustrating bout with an injury, one of the San Francisco 49ers veteran players is hinting at retirement.

In the San Francisco 49ers Week 14 contest against the Chicago Bears, the team will wear their customized cleats on the field ...

The San Francisco 49ers explored signing Tom Brady ahead of the 2023 season, a consideration that could repeat itself this ...