β-arrestins are known modulators of GPCR signaling, but their precise interaction with class B GPCRs is poorly understood. A new cryo-EM structure of a fully engaged parathyroid hormone receptor ...
The growing aging population is increasing the burden of neurodegenerative diseases, which highlights the need to understand disease heterogeneity for better management. Using a transformer-based ...
Economic issues continue to dominate Americans’ ranking of the country’s top problems. Meanwhile, the share who say illegal immigration is a very big problem has dropped since the start of Trump’s ...