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Many or most duplicon SNPs may be nothing more than paralogous sequence variants (PSVs) 3, 7, 8. Alternatively, gene conversion in duplicons may generate allelic diversity and SNP content 11, 12.
To discover SNPs, several copies of each locus must be sampled from a population and compared for sequence differences. Two methods have been described. The first, locus-specific polymerase chain ...
SNPs as Windows on Evolution Single nucleotide polymorphisms--variants in DNA sequences better known as SNPs and pronounced snips--provide a shortcut to comparing genes and genomes within and among ...
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Scientists discover novel receptor recognition mechanism for ... - MSNNotably, the VLDLR-W132G mutation was identified in human genome and SNP sequences, indicating that individuals with the W132G mutation may be more susceptible to infection by the EEEV alphavirus.
Since most SNPs are relatively rare, many genes between 2 individuals are identical, and therefore, one must genotype (determine the sequence of a variant DNA region) dozens of individuals before ...
A new map that delineates small genetic differences among people may be a powerful tool for figuring out why some individuals get certain diseases and how to customize their treatments.
More often than not, when a researcher needs to genotype samples for a particular single nucleotide polymorphism (SNP), or to measure the expression of a specific gene, they end up having to design ...
Sequence diversity in this Han Chinese genome, as indicated by the rate of autosomal heterozygosity in SNPs, was 6.94 × 10 ...
The SNPs that alter the DNA sequence in the control region, however, prevent this methylation from happening. This, in turn, results in the production of lactase because the gene is kept on.
In the new study, the researchers searched genome-wide data sets for cancer-related single-nucleotide polymorphisms (SNPs)—sequence variants affecting a single DNA nucleotide. In general, SNPs ...
In the new study, the researchers searched genome-wide data sets for cancer-related single-nucleotide polymorphisms (SNPs) -- sequence variants affecting a single DNA nucleotide.
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