Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...

HIV-1 Vpu triggers the cleavage of TDP-43 by stimulating Caspase 3 activation. The cleavage products generated can induce the ...

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Oxidative stress and the accompanying chronic inflammation constitute an important metabolic problem that may lead to pathology, especially when the body is exposed to physicochemical and biological ...

NLRP3 is an inflammasome seeding pattern recognition receptor activated in response to multiple danger signals which perturb intracellular homeostasis. Electrostatic interactions between the NLRP3 ...

According to a THP preliminary report, a tractor-trailer was traveling eastbound on I-40 near mile marker 412 just before 1 a.m. on Sunday when a pedestrian, identified as 45-year-old Tony Lee Ford, ...

UNICOI COUNTY, Tenn. (WJHL) – The Tennessee Highway Patrol (THP) responded to a crash on Thursday after a man allegedly evaded authorities in a vehicle, according to a report from the THP.

elegans) worm eats, the more slowly it loses fat. Now, scientists have discovered why: a small molecule produced by the worms' intestines during fasting travels to the brain to block a fat-burning ...

A certified sleep science coach and mattress expert, JD has been reviewing online mattresses professionally for the past five years. During that time, he's tested well over 150 beds and dedicated ...

According to THP, the crash happened at around 2 p.m. near Happy Hollow Road in Sevier County. THP said a Chevy Camaro was traveling eastbound in the westbound lane approaching a curve when it ...