BMJ

Plasminogen activation in synovial tissues: differences between normal, osteoarthritis, and rheumatoid arthritis joints

a Centre Hospitalier Universitaire Vaudois, Laboratoire de Rhumatologie, Lausanne, Switzerland , b Centre Medical Universitaire, Division d’Oncologie, Geneva, Switzerland Dr N Busso, Centre ...
BMJ

Studies with pain rating scales.

Good correlation has been shown between pain scores derived from 4 different rating scales. The correlation was maintained when presentation of the scales was separated by a series of questions and by ...
BMJ

Physiotherapy for anterior knee pain: a randomised controlled trial

OBJECTIVE To determine the efficacy of the individual components of physiotherapy in subjects with anterior knee pain. METHODS An observer blind, prospective, factorial design randomised controlled ...
BMJ

Temporary hold of mycophenolate augments humoral response to SARS-CoV-2 vaccination in patients with rheumatic and musculoskeletal diseases: a case series

Mycophenolate is the mainstay of treatment for many organ and life-threatening manifestations of rheumatic and musculoskeletal diseases (RMD). In contrast to most patients with RMD, those taking ...
BMJ

Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles

1 Department of Rheumatology, Leiden University Medical Centre, Leiden, Netherlands 2 Departments of Rheumatology and Epidemiology, Leiden University Medical Centre 3 Department of Immunohaematology ...
BMJ

European Scleroderma Study Group to define disease activity criteria for systemic sclerosis. III. Assessment of the construct validity of the preliminary activity criteria

Objective: To further assess the construct validity of the three European Scleroderma Study Group (EScSG) preliminary activity indices for systemic sclerosis (SSc): for SSc as a whole, for diffuse SSc ...
BMJ

Elevated circulating levels of interferon-γ and interferon-γ-induced chemokines characterise patients with macrophage activation syndrome complicating systemic juvenile ...

Objectives Interferon-γ (IFNγ) is the pivotal mediator in murine models of primary haemophagocytic lymphohistiocytosis (pHLH). Given the similarities between primary and secondary HLH (sec-HLH), ...
BMJ

Nottingham knee osteoarthritis risk prediction models

Objectives (1) To develop risk prediction models for knee osteoarthritis (OA) and (2) to estimate the risk reduction that results from modification of potential risk factors. Method This was a 12-year ...