Healthcare is undergoing a quiet revolution. Paper trails are giving way to digital records, and AI scribes are becoming official note-takers of patient–clinician conversations. This shift from ...

The growing use of genomic data in healthcare aims to balance predictive and diagnostic needs by supporting both disease prevention and clinical decision-making. Yet, the predictive potential of ...

We consider the ethical, regulatory and governance implications of emerging genomic technologies. Read our assessments of the impact of reform on the implementation of new health technologies and ...

A patient arriving in A&E or another clinical setting, with suspected or known infection and the risk of sepsis, requires immediate action. Antibiotic admission more than one hour after suspected ...

The sepsis definition describes three elements: infection, the host response and life-threatening organ dysfunction. Diagnosis is made based on myriad signs and symptoms, and although infection ...

Sepsis is a critical global healthcare challenge, marked by complex and rapidly evolving symptoms, which can escalate with alarming speed leading to multi-organ failure. This leaves only a narrow ...

The BMJ reviewed research on health test kits sold in UK supermarkets and uncovered some deeply concerning gaps. Unlike routine diagnostic tests and assays used in clinical practice and prescribed ...

Cost-utility studies provide critical information for the costs and benefits of using any new test, typically building on existing public health and screening programmes, within a defined population.

The Wellcome Trust recently announced that they are funding a research programme to investigate synthetic human genomes, and Laura Blackburn, PHG Foundation’s Head of Science, had the opportunity to ...

CAR-T is a powerful tool which is still evolving. Here we highlight what is new in CAR-T cell therapy Cancer cells often play hide-and-seek with the immune system in an attempt to evade catastrophic ...

The GenomeIndia Project, launched in 2020, represents a strategic effort to map India’s vast genetic diversity. It focuses on India’s rich tapestry of ethnolinguistic communities (Indo-European, ...

Antimicrobial resistance (AMR) is one of the greatest challenges facing health systems, causing an estimated 4.71 million deaths globally in 2021. It has been ten years since the World Health ...