One year ago, the PHG Foundation report, Host genomics: lessons for infectious diseases, highlighted the promise of host ...

The optimism is not unfounded. In specific, well-defined clinical scenarios, polygenic scores are beginning to demonstrate some tangible utility. For cardiovascular disease, MI-GENES, a 10-year follow ...

Catherine’s work focuses on the legal issues around migration, together with the legal and constitutional issues associated with Brexit, in particular examining the Withdrawal Agreement and the Trade ...

A patient arriving in A&E or another clinical setting, with suspected or known infection and the risk of sepsis, requires immediate action. Antibiotic admission more than one hour after suspected ...

The sepsis definition describes three elements: infection, the host response and life-threatening organ dysfunction. Diagnosis is made based on myriad signs and symptoms, and although infection ...

Sepsis is a critical global healthcare challenge, marked by complex and rapidly evolving symptoms, which can escalate with alarming speed leading to multi-organ failure. This leaves only a narrow ...

The term ‘mainstreaming’ was first used in 2003 by the Secretary of State for Health in the context of the genetics white paper Our Inheritance, Our Future when he argued that genomics must move from ...

The BMJ reviewed research on health test kits sold in UK supermarkets and uncovered some deeply concerning gaps. Unlike routine diagnostic tests and assays used in clinical practice and prescribed ...

Cost-utility studies provide critical information for the costs and benefits of using any new test, typically building on existing public health and screening programmes, within a defined population.

The Wellcome Trust recently announced that they are funding a research programme to investigate synthetic human genomes, and Laura Blackburn, PHG Foundation’s Head of Science, had the opportunity to ...

In a world first, the NHS has announced it is rolling out ‘blood-test first’ testing for patients with non-small cell lung cancer (NSCLC) in England. The tests have been added to the Genomic Test ...

The GenomeIndia Project, launched in 2020, represents a strategic effort to map India’s vast genetic diversity. It focuses on India’s rich tapestry of ethnolinguistic communities (Indo-European, ...