Dec 18, 2024 · Statins (also called HMG-CoA reductase inhibitors) block an enzyme called HMG-CoA reductase that is involved in making cholesterol. Specifically, statins block the synthesis …

Dec 3, 2025 · Lovastatin is a specific inhibitor of HMG-CoA reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate. The conversion of HMG-CoA to …

HMG-CoA Reductase Inhibitors General Statement reference guide for safe and effective use from the American Society of Health-System Pharmacists (AHFS DI).

Comprehensive disease interaction information for pravastatin systemic. Includes HMG-CoA reductase inhibitors - liver disease.

Sep 26, 2025 · There are no controlled data in human pregnancy. However, HMG-CoA reductase inhibitors are known to inhibit biosynthetic processes necessary in fetal development. Serum …

Sep 26, 2025 · Because HMG-CoA reductase inhibitors (statins) decrease cholesterol synthesis and possibly the synthesis of other biologically active substances derived from cholesterol, this …

Jul 2, 2025 · Two series of pregnant women who took an HMG-CoA reductase inhibitor (n=178 and n=134) during the first trimester of pregnancy, found serious fetal abnormalities in several …

Jun 12, 2025 · Rare cases of congenital anomalies after intrauterine exposure to HMG-CoA reductase inhibitors have been reported. There are no controlled data in human pregnancy.

Comprehensive disease interaction information for Zocor. Includes HMG-CoA reductase inhibitors - liver disease.

Oct 10, 2024 · Characterized by proximal muscle weakness and elevated CK concentrations that persist despite discontinuance of statin therapy, positive anti-HMG CoA reductase antibody, …