Treatment is aimed at keeping the blood clot from getting bigger and preventing new clots from forming. Prompt treatment is essential to prevent serious complications or death. Blood thinners or anticoagulants are the most common treatment for a blood clot in the lung. It is important to note that blood thinners won’t dissolve blood clots.

Treatment of a pulmonary embolism focuses on keeping the blood clot from getting bigger and preventing new clots from forming. Prompt treatment is essential to prevent serious complications or death. Treatment can include medicines, surgery and other procedures, and ongoing care.

Healthcare providers usually treat a PE in a hospital, where they can monitor your condition closely. The length of your pulmonary embolism treatment and hospital stay will vary, depending on the severity of the clot. Some people may not need to stay overnight. The main treatment for a pulmonary embolism is an anticoagulant (blood thinner).

Most patients with deep venous thrombosis or low-risk pulmonary embolism can be treated in the outpatient setting with low-molecular-weight heparin and a vitamin K antagonist (warfarin) or direct-acting oral anticoagulants. Inpatient treatment of VTE begins with parenteral agents, preferably low-molecular-weight heparin.